Publications
23.
An Oxidative C–H Functionalization/Anionic 6π Aza-Electrocyclization Approach to Protoberberine Alkaloids: Discovery of a New Class of AMPK Inhibitors
Cao, Y.; Trinh, A. Z.; Zhang, E.; Huang, W.; Kou, K. G. M.
Coming Soon.
22.
Direct Phenolic Alkylation of Unactivated Secondary Alcohols by Dual Zinc/CSA-Catalyzed Friedel-Crafts Reactions
Pan, A.; Nguyen, V. K.; Rangel, L.; Fan, C; Kou, K. G. M.
Cell Reports Physical Science, 2024, 5, 101886
21.
A Fenton Approach to Aromatic Radical Cations and Diarylmethane Synthesis
Crowley, R. III; Lujan, B.; Martinez, A.; Manasi, R.; DeBow, J. D.; Kou, K. G. M.
Journal of Organic Chemistry, 2023, 88, 15060-15066
20.
Synergistic Brønsted/Lewis Acid Catalyzed Aromatic Alkylation with Unactivated Tertiary Alcohols or Di-tert-Butylperoxide to Synthesize Quaternary Carbon Centers
Pan, A.; Chojnacka, M.; Crowley III, R.; Gottemann, L.; Haines, B.; Kou, K. G. M.
Chem. Sci., 2022, 13, 3539-3548
19.
The Biology and Total Syntheses of Bisbenzylisoquinoline Alkaloids
Nguyen, V. K.; Kou, K. G. M.
Org. Biomol. Chem., 2021, 19, 7535-7543
18.
α-Arylation of Silyl Enol Ethers via Rhodium(III)-Catalyzed C–H Functionalization
Kou, X., Kou, K. G. M.
ACS Catal., 2020, 10, 3103-3109
17.
Transition-Metal Catalyzed Hydroacylation In Organic Reactions
Dong, V. M.; Kou, K. G. M.; Le, D. N.
See the wiki article.
16.
A Copper-Mediated Conjugate Addition Approach to Analogs of Aconitine-Type Diterpenoid Alkaloids
Doering, N. A.; Kou, K. G. M.; Norseeda, K.; Lee, J. C.; Marth, C. J.; Gallego, G. M.; Sarpong, R.
J. Org. Chem., 2018, 83, 12911-12920
15.
A Benzyne-Insertion Approach to Hetisine-Type Diterpenoid Alkaloids: Synthesis of Cossoidine (Davisine).
Kou, K. G. M.*; Pflueger, J. J.* (equal contributions); Kiho, T.; Morrill, L. C.; Fisher, E. L.; Clagg, K.; Lebold, T. P.; Kisunzu, J. K.; Sarpong, R.
J. Amer. Chem. Soc., 2018, 140, 8105-8109
14.
Bio-inspired chemical synthesis of monomeric and dimeric stephacidin A congeners.
Mukai, K.; Pereira de Sant'Ana, D.; Hirooka, Y.; Mercado-Marin, E. V.; Stephens, D. E.; Kou, K. G. M.; Richter, S. C.; Kelley, N.; Sarpong, R.
Nat. Chem., 2018, 10, 38-44
- Highlighted in Synfacts 2018, 14, 341.
13.
A Unifying Synthesis Approach to the C₁₈-, C₁₉-, and C₂₀- Diterpenoid Alkaloids
Kou, K. G. M.; Kulyk, L.; Marth, C. J.; Lee, J. C.; Doering, N. A.; Li, B. X.; Gallego, G. M.; Lebold, T. P.; Sarpong, R.
J. Amer. Chem. Soc., 2017, 139, 13882-13896
12.
Syntheses of Denudatine Diterpenoid Alkaloids: Cochlearenine, N-Ethyl-1α-Hydroxy-17-Veratroyldictyzine, and Paniculamine.
Kou, K. G. M.; Li, B. X.; Lee, J. C.; Gallego, G. M.; Lebold, T. P.; DiPasquale, A. G.; Sarpong, R.
J. Am. Chem. Soc., 2016, 138, 10830-10833
- Highlighted in Synfacts 2016, 12, 1119.
- Highlighted in ACS Select Virtual Edition focused on natural products total synthesis.
11.
Network-analysis-guided synthesis of weisaconitine D and liljestrandinine.
Marth, C. J.; Gallego, G. M.; Lee, J. C.; Lebold, T. P.; Kulyk, S.; Kou, K. G. M.; Qin, J.; Lilien, R.; Sarpong, R.
Nature, 2015, 528, 493-498
10.
Rhodium(I)-Catalyzed Intermolecular Hydroacylation of α-Keto Amides and Isatins with Non-Chelating Aldehydes.
Kou, K. G. M.; Longobardi, L. E.; Dong, V. M.
Adv. Synth. Catal., 2015, 357, 2233-2237
9.
Rh-Catalyzed Desymmetrization of α-Quaternary Centers by Isomerization-Hydroacylation
Park, J.-W.; Kou, K. G. M.; Kim, D. K.; Dong, V. M.
Chem. Sci., 2015, 6, 4479-4483
- Highlighted in Synfacts 2015, 11, 1076.
8.
Tandem Rhodium Catalysis: Exploiting Sulfoxides for Asymmetric Catalysis (Perspective)
Kou, K. G. M.; Dong, V. M.
Org. Biochem. Chem., 2015, 13, 5844-5847
7.
Rh(I)-Catalyzed Intermolecular Hydroacylation: Enantioselective Cross-Coupling of Aldehydes and Ketoamides
Kou, K. G. M.; Le, D. N.; Dong, V. M.
J. Am. Chem. Soc., 2014, 136, 9471-9476
6.
Ligand-Controlled Switch: Regioselective Functionalization of Carbohydrate Derivatives
Chen, I.-H.; >Kou, K. G. M.; Le, D. N.; Rathbun, C. M.; Dong, V. M.
Chem - Eur. J., 2014, 20, 5013-5018
5.
Dynamic Kinetic Resolution of Allylic Sulfoxides: A Combined Experimental and Theoretical Mechanistic Study
Dornan, P. K.;* Kou, K. G. M.* (equal contributions); Houk, K. N.; Dong, V. M.
J. Am. Chem. Soc., 2014, 136, 291-298
4.
Oxygen-containing analogues of juvenile hormone III
Davies, K. A.; Kou, K. G. M.; Wulff, J. E.
Tetrahedron Lett., 2011, 52, 2302-2305
3.
Nitrogen-Directed Ketone Hydroacylation - An Enatioselective Synthesis of Benzoazepinones and Benzoazocinones
Khan, H. A.; Kou, K. G. M.; Dong, V. M.
Chem. Sci., 2011, 2, 407-410
2.
Enantioselective Desymmetrization of Cyclopropenes by Hydroacylation
Phan D. H. T.; Kou, K. G. M.; Dong, V. M.
J. Am. Chem Soc., 2010, 132, 16354-16355
- Highlighted in Synfacts 2011, 2, 192
1.
Regio- and Enantioselective Intermolecular Hydroacylation: Substrate-Directed Addition of Salicylaldehydes to Homoallylic Sulfides
Coulter, M.; Kou, K. G. M.; Galligan, B.; Dong, V. M.
J. Am. Chem. Soc., 2010, 132, 16330-16333
- Highlighted in Synfacts 2011, 2, 164
